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Airlines serving Roanoke include US Airways, United Express, Northwest Airlink and the Delta Connection carriers, Atlantic Southeast Airlines (ASA) and Comair.
Hotel Roanoke and Conference Center is located at 110 Shenandoah Ave., in Roanoke. Driving directions to the hotel are as follows.
- From North or South Interstate 81 — Take Exit 143 (I-581 South) to Exit 5. Bear right onto Wells Ave. Parking straight ahead.
- From U.S. Highway 220 North (Martinsville, VA) — 220 North becomes I-581 North. Take Exit 4E (Orange Ave.). Take first right at traffic light onto Williamson Rd. After the third traffic light, turn right on Shenandoah Ave. Take the first right to the main entrance of the hotel.
- From U.S. Highway 460 West (Lynchburg, VA) — 460 becomes Orange Ave. Turn left at the traffic light at Williamson Rd. and Orange Ave. After the third traffic light, turn right on Shenandoah Ave. Take the first right to the main entrance of the hotel.
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